Studies on the Enzymes
نویسندگان
چکیده
In the preceding paper (1) are recorded the facts so far obtained in a study of the proteolytic enzymes of pneumococcus. It has been shown that bile solutions of pneumococci, extracts obtained by disintegration of the organisms in phosphate mixtures, and sterile filtrates of autolyzing broth cultures possess the power to hydrolyze peptones and to a less extent certain intact proteins. In the present paper evidence will be presented that pneumococci possess also an endolipase of marked activity. The intracellular nature of this enzyme, the influence of age and hydrogen ion concentration on its activity, its thermostability, and relation to virulence and to the mechanism of bile solubility will be discussed.
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